Each episode of You're the Expert features an in-depth interview with a leading researcher. Past experts have included:

-Craig Mello, winner of the 2006 Nobel Prize in Medicine

-Margaret Geller, a MacArthur Genius

-Alexandra Horowitz, head of Barnard's Dog Cognition Lab

-Jessica Meir, an astronaut and comparative physiologist

-Phil Lobel, who studies the noises fish make

-Heather Berlin, a neuroscientist at Mt. Sinai who studies improvisation

-John Overholt, a rare books librarian at Harvard

-Caspar Hare, a normative ethicist

and many more.